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“I could not rest, Watson, I could not sit quiet in my chair, if I thought that such a man as Professor Moriarty were walking the streets of London unchallenged.”
― Arthur Conan Doyle

“Dr. Watson's summary list of Sherlock Holmes's strengths and weaknesses:

"1. Knowledge of Literature: Nil.
2. Knowledge of Philosophy: Nil.
3. Knowledge of Astronomy: Nil.
4. Knowledge of Politics: Feeble.
5. Knowledge of Botany: Variable. Well up in belladonna, opium, and poisons generally. Knows nothing of practical gardening.
6. Knowledge of Geology: Practical but limited. Tells at a glance different soils from each other. After walks has shown me splashes upon his trousers, and told me by their colour and consistence in what part of London he had received them.
7. Knowledge of Chemistry: Profound.
8. Knowledge of Anatomy: Accurate but unsystematic.
9. Knowledge of Sensational Literature: Immense. He appears to know every detail of every horror perpetrated in the century.
10. Plays the violin well.
11. Is an expert singlestick player, boxer, and swordsman.
12. Has a good practical knowledge of British law.”
― Arthur Conan Doyle, A Study in Scarlet

“Holmes and Watson are on a camping trip. In the middle of the night Holmes wakes up and gives Dr. Watson a nudge. "Watson" he says, "look up in the sky and tell me what you see."

"I see millions of stars, Holmes," says Watson.

"And what do you conclude from that, Watson?"

Watson thinks for a moment. "Well," he says, "astronomically, it tells me that there are millions of galaxies and potentially billions of planets. Astrologically, I observe that Saturn is in Leo. Horologically, I deduce that the time is approximately a quarter past three. Meterologically, I suspect that we will have a beautiful day tomorrow. Theologically, I see that God is all-powerful, and we are small and insignficant. Uh, what does it tell you, Holmes?"

"Watson, you idiot! Someone has stolen our tent!”
― Thomas Cathcart, Daniel Klein

“On glancing over my notes of the seventy odd cases in which I have during the last eight years studied the methods of my friend Sherlock Holmes, I find many tragic, some comic, a large number merely strange, but none commonplace; for, working as he did rather for the love of his art than for the acquirement of wealth, he refused to associate himself with any investigation which did not tend towards the unusual, and even the fantastic.”
― Arthur Conan Doyle